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John Wayne Casserole Recipe - This meaty, cheesy casserole is a hearty family meal solution!
4.46 from 57 ratings

John Wayne Casserole Recipe

This simple and hearty casserole recipe is a family favorite in my home!
Servings 6 -8 servings
Author Crissy Page

Ingredients

  • 2 pounds ground beef browned, crumbled and drained
  • 1 1 ounce packet taco seasoning
  • ¾ cups water
  • 1 small onion sliced thin in about 1 inch pieces
  • 1 red bell pepper sliced thin in about 1 inch pieces
  • 2 ¼ cups bisquick mix
  • cup water
  • ½ cup mayonnaise
  • ½ cup sour cream
  • 8 ounces sharp cheddar cheese shredded and divided
  • 2 roma tomatoes sliced thin
  • 1 4 ounce can green chiles

Instructions

  • Preheat oven to 325 degrees. Lightly spray a 9 x 13 inch glass baking dish with non-stick cooking spray.
  • In a 12-inch skillet brown the ground beef until thoroughly cooked, then drain and return to the skillet.  Add ¾ cup water, the taco seasoning packet and bring to a boil. Add the onion and the peppers. Turn down the heat and simmer for three to five minutes, or until  the onions and peppers begin to soften. Set aside
  • In  a small bowl mix together the biscuit mix and ⅔ cup water to make a soft dough. Press the dough into the bottom and up the sides about ½ inch in the prepared baking dish. The dough was a little sticky so I used parchment paper to press it out on the bottom and i used a spatula to bring it up the sides.
  • In a small bowl mix together the mayonnaise, the sour cream and half the cheese. Set aside.
  • Spread the ground beef mixture evenly over the biscuit layer. Evenly layer the sliced tomatoes over ground beef mixture. Evenly layer the green chilies over the tomatoes. Evenly spread the sour cream mixture over the green chilies. Top with remaining cheese.
  • Bake for 30 to 35 minutes or until edges are lightly browned.