I’ve been seeing variations of this recipe in church cookbooks for years, but, what is John Wayne casserole? After doing a little research on John Wayne casserole, I found an interesting story. For my family, this recipe is summed up in one word—DELICIOUS!

John Wayne Casserole Recipe
I’ve seen so many variations of John Wayne casserole over the years. Some of those variations have meat and some don’t.
I like to add ground beef to my John Wayne casserole, but you could certainly add ground turkey or skip the meat completely.
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It really just depends on what your family prefers.
Since I usually have a few pounds of ground beef in the freezer begging to be utilized, I love adding it to this recipe to create an easy and hearty weeknight meal.

Honestly, this casserole recipe usually looks like a big cheesy mess. I’m not going to lie! Luckily, this cheesy mess happens to taste absolutely amazing.
I was a tad bit skeptical the first time I put this John Wayne casserole together, and I can remember my husband giving me a bit of a side-eye, wondering what I was making.
One bite put our questions to rest. Even the kids enjoy this flavorful and simple family meal. I’m so glad that I finally gave this recipe a whirl. It has gone into our regular recipe rotation and my kiddos often ask for this recipe by name.
Well, they ask for “that one casserole with the weird guy’s name.” Haha! Maybe it’s time to introduce them to the John Wayne film archive.
Actually, maybe it’s time for ME to watch some John Wayne flicks. The Quiet Man was just recommended to me by one of the ladies in my Sunday school class. Is it as good as I’ve been told?
Back to the food! I think I’ve probably mentioned it more than once before, but, I’m just such a fan of casseroles, especially during the busy school year.
If you’re looking for more easy family recipes be sure to check out my tasty Mexican tater tot casserole, these simple ground turkey stuffed peppers, and my amazing chicken spaghetti recipe.
I hope you love my variation of John Wayne casserole!

John Wayne Casserole Recipe
Ingredients
- 2 pounds ground beef browned, crumbled and drained
- 1 1 ounce packet taco seasoning
- ยพ cups water
- 1 small onion sliced thin in about 1 inch pieces
- 1 red bell pepper sliced thin in about 1 inch pieces
- 2 ยผ cups bisquick mix
- โ cup water
- ยฝ cup mayonnaise
- ยฝ cup sour cream
- 8 ounces sharp cheddar cheese shredded and divided
- 2 roma tomatoes sliced thin
- 1 4 ounce can green chiles
Instructions
- Preheat oven to 325 degrees. Lightly spray a 9 x 13 inch glass baking dish with non-stick cooking spray.
- In a 12-inch skillet brown the ground beef until thoroughly cooked, then drain and return to the skillet. ย Add ยพ cup water, the taco seasoning packet and bring to a boil. Add the onion and the peppers. Turn down the heat and simmer for three to five minutes, or until ย the onions and peppers begin to soften. Set aside
- In ย a small bowl mix together the biscuit mix and โ cup water to make a soft dough. Press the dough into the bottom and up the sides about ยฝ inch in the prepared baking dish. The dough was a little sticky so I used parchment paper to press it out on the bottom and i used a spatula to bring it up the sides.
- In a small bowl mix together the mayonnaise, the sour cream and half the cheese. Set aside.
- Spread the ground beef mixture evenly over the biscuit layer. Evenly layer the sliced tomatoes over ground beef mixture. Evenly layer the green chilies over the tomatoes. Evenly spread the sour cream mixture over the green chilies. Top with remaining cheese.
- Bake for 30 to 35 minutes or until edges are lightly browned.

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The Quiet Man is my all time favorite John Wayne movie. In 2018 on a trip that included Ireland I was able to go where it was filmed. I have a picture sitting of me on the โJohn Wayneโ bridge. ย Looking forward to making this casserole.ย
This casserole was excellent! Did not have green chiles but added a layer of ย bacon. Very tasty. Thanks for the great recipe
I made this tonight for dinner. My family loved it but we all agreed that it was missing something. Next time I may use corn bread instead of the biscuit mix and I think adding corn and fire roasted tomatoes may give it a kick. It’s fun to experiment with a recipe.
This is a delicious recipe. i made it tonight for dinner and it was delicious. i used canned tomatoes and added sliced button mushrooms.
I just made this delicious casserole today. My husband and son loved it! I will make it many more times in the future. my changes: i used ground turkey and while it was browning i added 8 oz sliced button mushrooms, the red bell pepper, diced onions. after the veggies were tender i added a packet of mild taco seasoning then i added 1 each 14 oz. can of diced tomatoes, undrained. i didn’t add the water because the tomatoes provided enough liquid. I baked the biscuit crust 10 minutes by itself then i poured the skillet contents in it. then i followed the topping directions as in recipe and baked the casserole for 25 minutes. then i added the remaining cheese and put it back in the oven 5 min to melt the cheese. it was really delicious. thank you for the recipe and inspiration.
Donavan’s reef, Harti, Mc Clintock, the sons of Katie Elder, he has a lot of “must see” movies.ย
Years ago I belonged to a recipe chain letter. ย This one came from Marcia Sirringhra? ย
2 cans chopped green chiles, ย 1lb montery jack cheese, ย 1 lb. cheddar cheese, ย 4 egg yolks and whites, 2/3 cup evaporated milk, 1T flour,1/2 tsp. salt, 1/8 tsp. pepper, ย 2 tomatoes (garnish). ย Grate cheese into buttered ย glass casserole with chopped green chiles mixed in. ย Beat egg whites to stiff peaks (set ย aside). ย Mix together flour, ย salt, ย pepper ย and egg yolks with evaporated ย milk. ย Fold the egg mixture into egg whites. ย Pour over cheese and press in. ย Bake at 325 degrees for 30mins. ย Place tomato slices over top and bake for 30 mins. longer. ย YUM!!!!!