Preheat oven to 275.
In a large bowl add the cereal and pretzels.
In a small bowl add melted butter, brown sugar, pumpkin pie spice and vanilla. Pour over the dry mixture and stir to thoroughly coat.
Line a baking sheet with parchment paper and spread the mixture evenly.
Bake for 45 minutes, stirring well every 15 minutes.
Remove from oven and allow to cool thoroughly.
Toss with candy, store in an airtight container, enjoy!